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Steven Sanche

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Professeur adjoint

Faculté de pharmacie

steven.sanche@umontreal.ca

Expertises

Research projects Expand all Collapse all

Automated Population Pharmacokinetic Modeling Using Artificial Intelligence (AutoPopPK) Projet de recherche au Canada / 2026 - 2029

Funding sources: Université de Montréal
Grant programs: PINTERNE-F.Internes de Recherche - Démarrage en recherche (FDGEN061)

Systems-Level Modeling of Epstein–Barr Virus and Multiple Sclerosis Pathogenesis Projet de recherche au Canada / 2026 - 2029

Lead researcher : Steven Sanche
Funding sources: Université de Montréal
Grant programs: PINTERNE-F.Internes de Recherche - Démarrage en recherche (FDGEN061)

Publications Expand all Collapse all

Sanche S, Cassidy T, Chu P, Perelson AS, Ribeiro RM, Ke R. A simple model of COVID-19 explains disease severity and the effect of treatments. Scientific Reports. 2022;12.1:14210.

Lilley LM, Sanche S, Moore SC, Salemi MR, Vu D, Lyer S, Hengartner N, Mukunda H, (2022). Methods to capture proteomic and metabolomic signatures from cerebrospinal fluid and serum of healthy individuals. Scientific Reports. 2022; 12.1:13339.

Ruian K, Romero-Severson E, Sanche S, Hengartner N. Estimating the reproductive number R0 of SARS-CoV-2 in the United States and eight European countries and implications for vaccination. Journal of Theoretical Biology. 2021;517.

Kassem I, Sanche S, Li J, Bonnefois G, Dubé M-P, Rouleau J-L, Tardif J-C, White M, Turgeon J, Nekka F, de Denus S. Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure. Clinical and Translational Sciences. 2020;14(1):194-203.

Sanche S, Lin YT, Xu C, Romero-Severson E, Hengartner N, Ke R. Early Release-High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2. Emerg Infect Dis. 2020;26(7).

Rabanel JM, Adibnia V, Tehrani SF, Sanche S, Hildgen P, Banquy X, Ramassamy C. Nanoparticle heterogeneity: an emerging structural parameter influencing particle fate in biological media?. Nanoscale. 2019;11(2):383-406.

Sanche S, Mesplède T, Sheehan NL, Li J, Nekka F. Exploring an alternative explanation for the second phase of viral decay: Infection of short-lived cells in a drug-limited compartment during HAART. PloS one. 2018 Jul 17;13(7):e0198090.

Sanche S, Sheehan N, Mesplède T, Wainberg MA, Li J, Nekka F. A mathematical model to predict HIV virological failure and elucidate the role of lymph node drug penetration. CPT: pharmacometrics & systems pharmacology. 2017 Jul 1;6(7):469-76.

Landry S, Chen CN, Patel N, Tseng A, Lalonde RG, Thibeault D, Sanche S, Sheehan NL. Therapeutic drug monitoring in treatment-experienced HIV-infected patients receiving darunavir-based salvage regimens: A case series. Antiviral Research. 2018 Apr;152:111-116.

Fortin M, Haggerty J, Sanche S, Almirall J. Self-reported versus health administrative data: implications for assessing chronic illness burden in populations. A cross-sectional study. CMAJ open. 2017 Jul;5(3):E729-33.

Hudon C, Sanche S, Haggerty JL. Personal characteristics and experience of primary care predicting frequent use of emergency department: a prospective cohort study. PloS one. 2016 Jun 14;11(6):e0157489.

Rubinowicz A, Vedel I, Sanche S, Lortie M, Law S, Hughes J, Lapointe L. A portrait of electronic medical record use in primary care across Canada. Health Reform Observer–Observatoire des Réformes de Santé. 2016 Jun 1;4(2).

Jang Y, Lortie MA, Sanche S. Return on investment in electronic health records in primary care practices: a mixed-methods study. JMIR medical informatics. 2014 Jul;2(2):e25.

Voyer P, McCusker J, Cole MG, Monette J, Champoux N, Vu M, Ciampi A, Sanche S, Richard S, de Raad M. Feasibility and acceptability of a delirium prevention program for cognitively impaired long term care residents: A participatory approach. Journal of the American Medical Directors Association. 2014 Jan 1;15(1):77.e1-9.

Brunet A, Sanche S, Manetti A, Aouizerate B, Ribéreau-Gayon R, Charpentier S, Birmes P, Arbus C. Peritraumatic distress but not dissociation predicts posttraumatic stress disorder in the elderly. International psychogeriatrics. 2013 Jun;25(6):1007-12.

Poundja J, Sanche S, Tremblay J, Brunet A. Trauma reactivation under the influence of propranolol: an examination of clinical predictors. European Journal of Psychotraumatology. 2012 Dec 1;3(1):15470.

McCusker J, Tousignant P, Da Silva RB, Ciampi A, Lévesque JF, Vadeboncoeur A, Sanche S. Factors predicting patient use of the emergency department: a retrospective cohort study. Canadian Medical Association Journal. 2012 Jan 1;184(6):e307-16.

McCusker J, Roberge D, Lévesque JF, Ciampi A, Vadeboncoeur A, Larouche D, Sanche S. Emergency department visits and primary care among adults with chronic conditions. Medical care. 2010 Nov 1:972-80.

Bhat V, Grizenko N, Sanche S, Joober R. No relation between therapeutic response to methylphenidate and its cardiovascular side effects in children with attention-deficit/hyperactivity disorder. Clinical medicine. Pediatrics. 2008 Jan;1:CMPed-S1010.