50 dernières publications:

1. Deane AM, Lauzier F, Adhikari NKJ, Lamontagne F, Heels-Ansdell D, Thabane L, Williamson D, Kanji S, Barletta JF, Finfer S, Arabi Y, Ostermann M, Marshall J, Zytaruk N, Hardie M, Hammond N, Gyatt G, White K, Burns K, Dionne J, Young P, Cook D. Risk Factors for Patient-Important Upper Gastrointestinal Bleeding. Am J Resp Crit Care 2025;ePub 18 avril.
2. Martineau J, Bernard F, Gagnon A, Williams V, Araujo de Franca S, Williamson D, Cavayas YA. Variation in carbon dioxide is a stronger determinant of the brain tissue oxygenation than its synchronous value in critically ill patients with acute brain injury. Crit Care Explorations 2025;7:e1241.
3. Azimdadeh D, Lapierre A, Bouaouina Z, Williamson D, Mailhot T, Arbour C. ICU nurses’ perspectives on family involvement in delirium care for postoperative cardiac surgery patients. Intensive Crit Care Nursing 2025;88:104001.
4. St-Jean I, Hachemi D, Friciu M, Forest JM, Belliveau M, Williamson D, Leclair G. Stability of dexmedetomidine, ketamine and lidocaine combined injectable solution. Eur J Hosp Pharm 2025;ePub 5 mars.
5. Beaucage-Charron J, Rinfret J, Trottier G, Sevigny MM, Burry L, Marsot A, Williamson D. Pharmacokinetics of opioid infusions in the intensive care unit setting – A systematic review. Clin Pharmacokinetics 2025;ePub 1 mars.
6. Brazeau D, Deshaies AA, Williamson DR, Bernard F, Arbour C, Lavigne G, Pinard AM, Rouleau D, de Beaumont L. Impact of an acute 1-month cannabidiol treatment on pain and inflammation after a long bone fracture: a triple-blind randomized, placebo controlled, clinical trial protocol. BMJ Open 2025;15:e092919.
7. Saavedra-Mitjans M, David PM, Arbour C, Perreault M, Roux M, Frenette AJ, Khwaja K, Bernard F, Williamson DR. EXperienceS and percepTions towards Agitated behaviours in Tbi ICu patients: qualitative interviews with nurses. Brain Injury 2025;ePub Feb 3rd
8. Burry LD, Williamson DR, Detsky M, Bernard F, Mehta S, Scales D, Rose L. Feasibility of melatonin for prevention of delirium in critically ill patients. Chest 2025;ePub Jan 10^th
9. Daoust R, Paquet J, Williamson D, Huard V, Arbour C, Perry JJ, Emond M, Berthelot S, Archambault P, Rouleau D, Morris J, Cournoyer. Impact of Vitamin C on the Reduction of Opioid Consumption for Acute Musculoskeletal Pain: A Double-Blind Randomized Control Pilot Study. Plos One 2024;19:e0316450.
10. Massé O, Mercurio CM, Dupuis S, Arruda A, Desforges K, Dugré N, Dallaire G, Williamson DR. Calcium and/or vitamin D to prevent fractures and falls in older adults: Protocol for a systematic review and meta-analysis. BMJ Open 2024;14:e085902.
11. Lapierre, A., Bérubé, M., Giroux, M., Tardif, P.-A., Turcotte, V., Mercier, É., Richard-Denis, A., Williamson, D., & Moore, L. (2024). Interprofessional interventions that impact collaboration and quality of care across inpatient trauma care continuum: A scoping review. Injury, 55(11), 111873.
12. Mohktari KW, Wong A, Nguyen M, Giard A, Ly B, Wazzan D, Williamson D, Dagenais-Beaulé V. Post-discharge opioid prescription and consumption in surgical inpatients: the POPCORN observational Study. Can J Hosp Pharmacy 2024;77:e3574.
13. Dahel H, Burry L, Tabbara N, Williamson D, Hornstein G, Wang HT. Optimizing Subsequent CARdiovascular Medication Re-introduction in the Intensive Care Unit (OSCAR-ICU). Can J Kidney Disease 2024;11:Sept 5^th.
14. Daoust R, Paquet J, Emond M, Iseppon M, Williamson D, Yan J, Perry JJ, Huard V, Lavigne G, Lee J, Lessard J, Lang E, Cournoyer A. Opioids for acute pain: how much to prescribe to minimize unused medication? (OPUM Study). CMAJ 2024;196:E866-E874.
15. Wang Y, Parpia S, Ge L, Heels-Ansdell D, Lai H, Esfahani MA, Pan E, Alhazzani W, Schandelmaier S, Lauzier F, Arabi Y, Barletta J, Deane A, Finfer S, Williamson D, Kanji S, Moller MH, Perner A, Krag M, Young PJ, Dionne JC, Hammond N, Ye Z, Ibrahim Q, Cook, D. Proton Pump Inhibitors for Prophylaxis Against Gastrointestinal Bleeding in Critically Ill Patients: A Systematic Review with Meta-Analysis. NEJM Evidence 2024. ePub June 14th
16. Cook D, Dean A, Lauzier F, Zytaruk N, Guyatt G, Saunders L, Hardie M, Heels-Ansdell D, Alhazzani W, Marshall J, Muscedere J, Myburgh J, English S, Arabi Y, Ostermann M, Knowles S, Hammond N, Byrne KM, Chapman M, Venkatesh B, Young P, Rajbhandari D, Poole A, Al Fares A, Reis G, Johnson D, Iqbal M, Hall R, Meade M, Hand L, Duan E, Clarke F, Dionne JC, Tsang JLY, Rochwerg B, Karachi T, Lamontagne F, D’Aragon F, St-Arnauld C, Reeve B, Geagea A, Niven F, Vasquez-Grande G, Zarychanski R, Ovakim D, Wood G, Burns K, Goffi A, Wilcox E, Henderson W, Forrest D, Fowler R, Adhikari N, Ball I, Mele T, Binnie A, Trop S, Mehta S, Morgan I, Loubani O, Vanstone M, Fiest K, Charbonney E, Cavayas A, Archambault P, Rewa O, Lau V, Kristoff AS, Khwaja K, Williamson D, Kanji S, Sy E, Dennis B, Reynolds S, Marquis F, Lellouche F, Rahman A, Hosek P, Barletta J, Cirone R, Tutschka M, Xie F, Billot L, Thabane L, Finfer S, for the REVISE Trial Investigators. Stress Ulcer Prophylaxis for Invasively Ventilated Patients: A Randomized Trial. N Engl J Med 2024. ePub June 14th
17. Burry LD, Bell C, Hill A, Pinto R, Scales D, Bronskill S, Rose L, Williamson D, Fowler R, Wunsch H. Trends in Sedative Prescription Among Older Adults after Critical Illness: A Population-Based Cohort Study. Am J Resp Crit Care 2024;ePub June 11^th
18. Lapierre A, Proulx A, Gélinas C, Dollé S, Alexander S, Williamson D, Bernard F, Arbour C. Association between pupil light reflex measurements during mechanical ventilation and post-extubation delirium in adults with traumatic brain injury: Preliminary findings. J Neuroscience Nursing 2024:ePub June 3^rd.
19. Saavedra-Mitjans, M., Van der Maren, S., Gosselin, N., Duclos, C., Frenette, A. J., Arbour, C., … Williamson, D. R. (2024). Use of actigraphy for monitoring agitation and rest-activity cycles in patients with acute traumatic brain injury in the ICU. Brain Injury, 1–7.
20. Cataford G, Monton LA, Karzon S, et al. Cognitive and motor function effects of antipsychotics in traumatic brain injury: a systematic review of pre-clinical studies. Neurotrauma Reports 2024:5(1):181–193.
21. El-Hattaf I, Marsot A, Hachemi D, Pesout T, Williams V, Smith MA, Albert M, Williamson D. Exposure Levels and Target Attainment of Piperacillin/Tazobactam in Intensive Care Unit Adult Patients: a Prospective Observational Study. Can J Anesth 2024;ePub Jan 19^th.
22. Saavedra-Mitjans M, Frenette AJ, McCredie V, Arbour C, Charbonney E, Albert M, Mehta S, Wang HT, Burry L, Bernard F, Williamson D. ICU physicians’ beliefs and perceived importance of agitation in TBI patients: A survey of Canadian intensivists. Can J Anesth 2024;71:264-73.
23. White G, Adessky N, Chen FW, Regazzoni A, Tourian L, Chagnon M, Gursahaney A, Roux M, Alharbi M, Williamson D, Perreault. Impact Of Valproic Acid For Agitation In The Intensive Care Unit: a Retrospective Analysis Of Psychiatric Consults. Int J Clin Pharm 2024;1:177-85.
24. Leclerc C, Gervais C, Hjeij D, Briand MM, Williamson D, Bernard F, Duclos C, Arbour C. Sleep in hospitalized adults sustaining a traumatic brain injury: A scoping review. J Head Trauma Rehab 2023;ePub 28 sept
25. D’Amours M, Ettis F, Ginefri L, Lim J, Lin Poo Yuan A-S, Fontaine J, Wazzan D, Williamson D, Dagenais-Beaulé V. A pilot study to improve geriatric care through a pharmacist-led psychotropic stewardship program. Drugs and Aging 2023; 40:1037-1045.
26. El-Hattaf I, Laverdière J, Albert M, Marsot A, Williamson D. Potential Benefits of Therapeutic Drug Monitoring for Beta-lactam Antibiotics in Augmented Renal Clearance Patients: A Case Report. Canadian Journal of Physiology and Pharmacology 2023;102:69-74.
27. Daoust R, Paquet J, Marquis M, Williamson D, Fontaine G, Chauny JM, Frégeau A, Orkin A, Cournoyer A. Efficacy and Safety of Prescribed Opioids for Acute Pain after Being Discharged from the Emergency Department: A Systematic Review. 30:1253-1263.
28. Duceppe MA, Kanji S, Ruo N, Do A, Cavayas YA, Robert-Halabi M, Albert M, Zavalkoff S, Samoukovic G, Williamson DR. Alterations in the pharmacokinetics and pharmacodynamics of commonly used antimicrobials in pediatric critical care patients during extracorporeal membrane oxygenation: A systematic review. Pediatric Drugs 2023;25:515-535
29. Daoust R, Paquet J, Chauny JM, Williamson D, Huard V, Arbour C, Emond M, Rouleau D, Cournoyer A. Impact of Vitamin C on the Reduction of Opioid Consumption After an Emergency Department Visit for Acute Musculoskeletal Pain: A Double-Blind Randomized Control Trial Protocol. BMJ Open 2023;13:e699230.
30. Kanji S, Williamson D, Hartwick M. Pharmacological confounders in the setting of brain death declaration. Can J Anesth 2023;70:713-23.
31. Beaucage-Charron J, Rinfret J, Coveney R, Williamson D. Melatonin and Ramelteon in the Treatment of Delirium: A Systematic Review and Meta-analysis. J Psychomatic Res 2023;170:111345.
32. Ouerd S, Frenette AJ, Williamson D, Serri K, D’Aragon F, Meade M, Bichet D, Charbonnney E. Vasopressin use in organ donors: a narrative review of the literature and evidences. Crit Care Explorations 2023;5:e0907
33. Flynn F, Dobrescu MA, Richard G, Hassan C, Pigeon M, Chagnon M, Charbonney E, Serri K, D’Aragon F, Weiss MJ, Williamson DR, Frenette AJ. Self-perceived role and knowledge of community pharmacists in organ donation. Int J Clin Pharm 2023;45:748-57.
34. Duquet-Armand M, Bouziane A, Arruda A, Denault JS, Routhier A, Cusson T, Halwagi A, Williamson D, Perreault M, Lordkipanidzé, Létourneau-Guillon L, Thiboutot Z. Spontaneous intracranial hemorrhage and oral anticoagulation: a retrospective study. Can Journ Gen Int Med 2023;18:54-65.
35. Duong A, Simard C, Williamson D, Marsot A. Tobramycin a priori dosing regimens based on PopPK model’s simulations in critically ill patients: are they transferable? Ther Drug Monit 2023;45:616-622
36. Dionne JC, Johnstone J, Heels-Ansdell D, Duan E, Lauzier F, Arabi YM, Adhikari NKJ, Sligl W, Dodek P, Rochwerg B, Marshall JC, Niven DJ, Williamson DR, Reynolds S, Zytaruk N, Cook D.Clostridioides Difficile Infection in Mechanically Ventilated Critically Ill Patients: A Nested Cohort Study. J Crit Care 2023; 75:154254.
37. Burry LD, Bell C, Hill A, Pinto R, Scales DC, Bronskill SE, Williamson D, Rose L, Fu L, Fowler R, Martin CM, Dolovich L, Wunsch H. New and persistent sedative prescription after critical illness among older adults: A population-based cohort study. Chest 2023;163:1425-36.
38. Hardy A, Beetz G, Chamali K, Courgeon M, Sandman E, Williamson D, Goetti P, Leduc S, de Beaumont L, Rouleau DM. Traumatic Brain Injuries in Proximal Humeral or Clavicle Fractures Studies: The Missing Link – A Systematic Review. International Orthopedics 2023;47:17-50.
39. Daoust R, Paquet J, Williamson D, Perry J, Iseppon M, Castonguay V, Morris J, Cournoyer A. Accuracy of a Self-Report Prescription Opioid Use Diary for Patients Discharge from the Emergency Department with Acute Pain. BMJ Open 2022;12:e062984.
40. Duong A, Simard C, Williamson D, Marsot A. Model re-estimation: an alternative for poor predictive performance during external evaluations? Example of gentamicin in critically ill patients. Pharmaceutics 2022 ;14:1426.
41. Marsolais P, Larouche G, Lagacé AM, Williams V, Bernard F, Rico P, Frenette AJ, Williamson D, Albert M, Charbonney E. The feasibility of potential organ donors using real case-scenarios; do we need to create a “donor board” process for donors perceived as unlikely feasible? Transplant Intl 2022;35:10107.
42. Duong A, Simard C, Williamson D, Thirion D, Marsot A. Aminoglycosides’ dosing and monitoring practices in intensive care unit settings in Quebec. J Chemother 2022; 34:341-44.
43. Chan C, Burry L, Tse C, de Castro C, Wunsch H, Williamson D. Impact of ketamine analgosedation on outcomes in critically ill patients: Systematic review and meta-analysis. Ann Pharmacother 2022; 56:1139-1158
44. Daoust R, Paquet J, Marquis M, Chauny JM, Williamson D, Huard V, Arbour C, Émond M, Cournoyer A. Evaluation of Interventions to Reduce Opioid Prescribing for Patients Discharged From the Emergency Department: A Systematic Review and Meta-analysis. JAMA Netw Open. 2022;5(1):e2143425.
45. Martineau-Lessard, C., Arbour, C., Germélus, N-É., Williamson, D., De Beaumont, L., Bernard, F. Pupil light reflex for the assessment of analgesia in critically ill sedated patients with traumatic brain injury: A preliminary study. Journal of Neuroscience Nursing 2022;54:6-12.
46. Daoust R, Paquet J, Huart V, Chauny JM, Lavigne G, Williamson D, Choiniere M, Lang E, Yan JW, Perry JJ, Emond M, Gosselin S, Cournoyer A. Association Between Fentanyl Treatment for Acute Pain in the Emergency Department and Opioid Use Two Weeks After Discharge. Am J Emerg Med 2022;52:137-142.
47. Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi Y, Heels-Ansdell D; Thabane L, Lamarche D; Surette M; Zytaruk N, Mehta S, Dodek, P, Mcintyre L, English S; Rochwerg B,Karachi T, Henderson W, Wood G, Ovakim D, Herridge M, Granton J, Wilcox E, Gioffi A, Stelfox H; Niven D, Muscedere, J, Lamontagne F, D'Aragon, F, St-Arnaud C, Ball I, Nagpal D, Girard M, Aslanian P, Charbonney E, Williamson D, Sligl W, Friedrich J, Adhikari N; Marquis F, Archambault P, Khwaja K, Kristof A, Kutsiogiannis J, Zarychanski R, Paunovic, B, Reeve B, Lellouche F, Hosek P, Tsang J, Binnie A, Trop S, Loubani O, Hall R, Cirone R, Reynolds S, Lysecki P, Golan E, Carten Ceba R, Taylor R, Cook D. Lactobacillus Rhamnosus GG in Critical Illness: A Randomized Trial. JAMA 2021;326:1024-33.
48. Burry L, Chen W, Williamson D, Guenette M, Hutton B, Mehta S, Egerod I, Kanji S, Adhikari NK, Moher D, Martin C, Rose L. Intensive Care Med 2021;47:943-60.
49. Duceppe MA, Kanji S, Ruo N, Do A, Cavayas YA, Robert-Halabi M, Albert M, Zavalkoff S, Samoukovic G, Williamson DR. Alterations in the pharmacokinetics and pharmacodynamics of commonly used antimicrobials in critical care patients during extracorporeal membrane oxygenation: A systematic review. Drugs. 2021;81:1307-1329.